Just Plain Ruff Posted February 4, 2014 Posted February 4, 2014 File Name: Glucagon and Cardiac Arrest File Submitter: Ruffmeister Paramedic File Submitted: 04 Feb 2014 File Category: Cardiac A Promising study. Click here to download this file
rock_shoes Posted February 6, 2014 Posted February 6, 2014 Thanks Ruff. Looks like an interesting article. It should round out my between call reading at work tomorrow.
rock_shoes Posted December 5, 2014 Posted December 5, 2014 Have you come across any follow up to this study Ruff?
Just Plain Ruff Posted December 6, 2014 Author Posted December 6, 2014 Nope but I haven't really looked, Rockshoes - Work has been killing me since I posted this.
rock_shoes Posted December 6, 2014 Posted December 6, 2014 No worries. My service is heavily involved in the various ROC studies and I was wondering if enough evidence had been collected to suggest it as a new trial once we're finished with ALPS (Amiodarone Lidocaine or Placebo (saline)).
mikeymedic1984 Posted December 12, 2014 Posted December 12, 2014 All I can say is that we had a lot more Returns of Circulation (not necessarily discharges from hospital) when we started every arrest patient off with a round of bicarb, D50, and Epi.
triemal04 Posted December 12, 2014 Posted December 12, 2014 No worries. My service is heavily involved in the various ROC studies and I was wondering if enough evidence had been collected to suggest it as a new trial once we're finished with ALPS (Amiodarone Lidocaine or Placebo (saline)). I think that what you'll see is either a intubation study (maybe, but if some groups dropped out that could, and hopefully WOULD kill that study) or one done on various doses of epinephrine. My personal opinion only on the latter but...wouldn't surprise me. All I can say is that we had a lot more Returns of Circulation (not necessarily discharges from hospital) when we started every arrest patient off with a round of bicarb, D50, and Epi. Sure you did.
ERDoc Posted December 13, 2014 Posted December 13, 2014 I would like to have seen a glucagon only arm. With all of these studies with poorer outcomes with epi, you have to wonder if epi isn't the problem.
triemal04 Posted December 13, 2014 Posted December 13, 2014 I would like to have seen a glucagon only arm. With all of these studies with poorer outcomes with epi, you have to wonder if epi isn't the problem. I doubt glucagon will be studied in any large way anytime soon, but who knows. Epi, on the other hand, is worth looking at, especially since the most recent bullshit study from Japan (I honestly don't understand why those get published in the form they were in) and some other smaller, poorly run ones have come out. I think that if a true randomized study is ever done it'll probably show, not that epi is bad, but that it is most effective and has the highest benefit when given early (as the Japanese study actually showed), and most likely doesn't need to be given in the same massive doses that it's given now. That and that at some point we need to come around to understanding that a lot of people who go into cardiac arrest did so for a reason, and should be allowed to remain that way. Mikey...this is a discussion for adults. Go sit in the corner and observe.
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